| ncRNA name | hsa-miR-181c |
| ncRNA Category | miRNA |
| Disease name | retinoblastoma (RB) |
| Species | Homo sapiens |
| Tissues/Cell_line | RB samples, non-neoplastic retinas; RB cell lines Y79 and WERI-RB1 |
| Methods | siRNA transfection, microarray, qRT-PCR, MTT assay, flouorometric caspase-3 assay, matrigel invasion assay, Western blot |
| Expression pattern | up-regulated |
| Functional description | EpCAM regulated miR-181c and miR-130b may play significant roles in RB progression. Treatment with anti-miR-181c and miR-130b showed significant decrease in cell viability and cell invasion. |
| PubMed ID | 25502397 |
| Year | 2014 |
| Title | EpCAM knockdown alters microRNA expression in retinoblastoma--functional implication of EpCAM regulated miRNA in tumor progression. |
| Drug-related ncRNA | NO |
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